RelativeHybridTopologyProtocolSettings#

pydantic model openfe.protocols.openmm_rfe.RelativeHybridTopologyProtocolSettings#

Configuration object for RelativeHybridTopologyProtocol

Create a new model by parsing and validating input data from keyword arguments.

Raises ValidationError if the input data cannot be parsed to form a valid model.

field forcefield_settings: OpenMMSystemGeneratorFFSettings [Required]#

Parameters to set up the force field with OpenMM Force Fields.

field thermo_settings: ThermoSettings [Required]#

Settings for thermodynamic parameters.

field system_settings: SystemSettings [Required]#

Simulation system settings including the long-range non-bonded method.

field solvation_settings: SolvationSettings [Required]#

Settings for solvating the system.

field alchemical_settings: AlchemicalSettings [Required]#

Alchemical protocol settings including lambda windows and soft core scaling.

field alchemical_sampler_settings: AlchemicalSamplerSettings [Required]#

Settings for sampling alchemical space, including the number of repeats.

field engine_settings: OpenMMEngineSettings [Required]#

Settings specific to the OpenMM engine such as the compute platform.

field integrator_settings: IntegratorSettings [Required]#

Settings for the integrator such as timestep and barostat settings.

field simulation_settings: SimulationSettings [Required]#

Simulation control settings, including simulation lengths and record-keeping.